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Article

CCL2 promoter hypomethylation is associated with gout risk in Chinese Han male population.

Immunology letters - 1 Oct 2017

Li Bin, Chen Xiaoying, Jiang Yuting, Yang Yong, Zhong Jie, Zhou Cong, Hu Haochang, Duan Shiwei

Abstract excerpt

OBJECTIVES: C-C motif chemokine ligand 2 (CCL2) encodes a chemokine which amplifies and maintains inflammation through chemokine-cytokine networks. Gout is a type of painful inflammation arthritis in response to the deposition of monosodium urate (MSU) crystals in joints. The purpose of this study was to figure out the role of CCL2 promoter methylation in gout. METHODS: A quantitative methylation-specific...

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Source

Identifiers

PMID: 28690186
DOI: 10.1016/j.imlet.2017.06.011

Genes

CCL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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