Article
Functional polymorphisms of the ABCG2 gene are associated with gout disease in the Chinese Han male population.
International journal of molecular sciences - 22 May 2014
Zhou Danqiu, Liu Yunqing, Zhang Xinju, Gu Xiaoye, Wang Hua, Luo Xinhua, Zhang Jin, Zou Hejian, Guan Ming
Abstract excerpt
BACKGROUND: Gout is a common type of arthritis that is characterized by hyperuricemia, tophi and joint inflammation. Genetic variations in the ABCG2 gene have been reported to influence serum uric acid levels and to participate in the pathogenesis of gout, but no further data have been reported in the Han Chinese population. METHODS: Peripheral blood DNA was isolated from 352 male patients with gout and 350...
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