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Article

A common variant of MAF/c-MAF, transcriptional factor gene in the kidney, is associated with gout susceptibility.

Human cell - 1 Jan 2018

Higashino Toshihide, Matsuo Hirotaka, Okada Yukinori, Nakashima Hiroshi, Shimizu Seiko, Sakiyama Masayuki, Tadokoro Shin, Nakayama Akiyoshi, Kawaguchi Makoto, Komatsu Mako, Hishida Asahi, Nakatochi Masahiro, Ooyama Hiroshi, Imaki Junko, Shinomiya Nariyoshi

Abstract excerpt

Gout is a multifactorial disease characterized by acute inflammatory arthritis, and it is caused as a consequence of hyperuricemia. A recent meta-analysis of genome-wide association studies has newly identified the relationship between serum uric acid (SUA) levels and rs889472, a single nucleotide polymorphism of musculoaponeurotic fibrosarcoma oncogene (MAF/c-MAF). However, it remained unclear whether rs889472...

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Identifiers

PMID: 29080939
DOI: 10.1007/s13577-017-0186-6

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MAF

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