Article
Polymorphisms -1082 G/A and -819 C/T in the interleukin-10 gene are not associated with gout susceptibility in the Chinese Han male population.
Genetic testing and molecular biomarkers - 1 Aug 2012
Liu Shiguo, Zhang Kun, Yin Congcong, Han Lin, Sun Yuping, Ren Wei, Chu Nan, Li Changgui
Abstract excerpt
BACKGROUND: Gout is caused by monosodium urate crystal-induced inflammation of the joints and periarticular tissues. Interleukin 10 (IL-10) is an important immunoregulatory cytokine, levels of which can be influenced by functional single-nucleotide polymorphisms in the promoter. OBJECTIVE: To investigate the association of -1082 G/A and -819 C/T polymorphisms in the IL-10 promoter with gout susceptibility in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
