Article
The CC chemokine ligand 2 (CCL2) polymorphism -2518A/G is associated with gout in the Chinese Han male population.
Rheumatology international - 1 Mar 2015
Sun Ruixia, Zhang Keke, Zhang Xiaokun, Cui Lingling, Wang Can, Mi Qingsheng, Liu Shiguo, Li Changgui
Abstract excerpt
Gout is usually characterized by uric acid-induced recurrent attacks of acute inflammatory arthritis. CC chemokine ligand 2 (CCL2), a chemokine involved in the recruitment and migration of monocytes/macrophages, has previously been shown to be increased in the plasma of gout patients. In this study, we examined whether the CCL2 -2518A/G (rs1024611) single nucleotide polymorphism (SNP) affects susceptibility to...
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