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Article

Opportunities and challenges in phenotypic drug discovery: an industry perspective.

Nature reviews. Drug discovery - 1 Aug 2017

Moffat John G, Vincent Fabien, Lee Jonathan A, Eder Jörg, Prunotto Marco

Abstract excerpt

Phenotypic drug discovery (PDD) approaches do not rely on knowledge of the identity of a specific drug target or a hypothesis about its role in disease, in contrast to the target-based strategies that have been widely used in the pharmaceutical industry in the past three decades. However, in recent years, there has been a resurgence in interest in PDD approaches based on their potential to address the...

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PMID: 28685762
DOI: 10.1038/nrd.2017.111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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