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Article

Recent advances in phenotypic drug discovery.

F1000Research - 1 Jan 2020

Swinney David C, Lee Jonathan A

Abstract excerpt

There is a great need for innovative new medicines to treat unmet medical needs. The discovery and development of innovative new medicines is extremely difficult, costly, and inefficient. In the last decade, phenotypic drug discovery (PDD) was reintroduced as a strategy to provide first-in-class medicines. PDD uses empirical, target-agnostic lead generation to identify pharmacologically active molecules and novel...

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PMID: 32850117
DOI: 10.12688/f1000research.25813.1
PMCID: PMC7431967

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