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Article

Gene Variations of Sixth Complement Component Affecting Tacrolimus Metabolism in Patients with Liver Transplantation for Hepatocellular Carcinoma.

Chinese medical journal - 20 Jul 2017

Liao Jian-Hua, Li Chang-Can, Wu Shao-Han, Fan Jun-Wei, Gu Hai-Tao, Wang Zhao-Wen

Abstract excerpt

BACKGROUND: Orthotopic liver transplantation (OLT) improves the prognosis of patients with hepatocellular carcinoma (HCC). Moreover, the complement system is a powerful immune effector that can affect liver function and process of liver cirrhosis. However, studies correlating the complement system with tacrolimus metabolism after OLT are scarce. In this study, the role of single nucleotide polymorphisms (SNPs)...

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Identifiers

PMID: 28685716
DOI: 10.4103/0366-6999.209886
PMCID: PMC5520553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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