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Article

Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations.

Scientific reports - 5 Jul 2017

Kumar Vijay, Rahman Safikur, Choudhry Hani, Zamzami Mazin A, Sarwar Jamal Mohammad, Islam Asimul, Ahmad Faizan, Hassan Md Imtaiyaz

Abstract excerpt

Protein stability is a requisite in the field of biotechnology, cell biology and drug design. To understand effects of amino acid substitutions, computational models are preferred to save time and expenses. As a systemically important, highly abundant, stable protein, the knowledge of Cu/Zn Superoxide dismutase1 (SOD1) is important, making it a suitable test case for genotype-phenotype correlation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28680046
DOI: 10.1038/s41598-017-04950-9
PMCID: PMC5498623

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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