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Article

Computing stability effects of mutations in human superoxide dismutase 1.

The journal of physical chemistry. B - 20 Feb 2014

Kepp Kasper P

Abstract excerpt

Protein stability is affected in several diseases and is of substantial interest in efforts to correlate genotypes to phenotypes. Superoxide dismutase 1 (SOD1) is a suitable test case for such correlations due to its abundance, stability, available crystal structures and thermochemical data, and physiological importance. In this work, stability changes of SOD1 mutations were computed with five methods, CUPSAT,...

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Identifiers

PMID: 24472010
DOI: 10.1021/jp4119138

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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