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Article

Directed evolution of cell size in Escherichia coli.

BMC evolutionary biology - 17 Dec 2014

Yoshida Mari, Tsuru Saburo, Hirata Naoko, Seno Shigeto, Matsuda Hideo, Ying Bei-Wen, Yomo Tetsuya

Abstract excerpt

BACKGROUND: In bacteria, cell size affects chromosome replication, the assembly of division machinery, cell wall synthesis, membrane synthesis and ultimately growth rate. In addition, cell size can also be a target for Darwinian evolution for protection from predators. This strong coupling of cell size and growth, however, could lead to the introduction of growth defects after size evolution. An important...

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Identifiers

PMID: 25514845
DOI: 10.1186/s12862-014-0257-1
PMCID: PMC4279887

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