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Article

Abnormal respiration under hyperoxia in TASK-1/3 potassium channel double knockout mice.

Respiratory physiology & neurobiology - 1 Oct 2017

Buehler Philipp K, Bleiler Doris, Tegtmeier Ines, Heitzmann Dirk, Both Christian, Georgieff Michael, Lesage Florian, Warth Richard, Thomas Jörg

Abstract excerpt

Despite intensive research, the exact function of TASK potassium channels in central and peripheral chemoreception is still under debate. In this study, we investigated the respiration of unrestrained TASK-3 (TASK-3-/-) and TASK-1/TASK-3 double knockout (TASK-1/3-/-) adult male mice in vivo using a plethysmographic device. Ventilation parameters of TASK-3-/- mice were normal under control condition (21% O2) and...

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Identifiers

PMID: 28673876
DOI: 10.1016/j.resp.2017.06.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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