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Article

The in vivo respiratory phenotype of the adenosine A1 receptor knockout mouse.

Respiratory physiology & neurobiology - 1 Feb 2016

Heitzmann Dirk, Buehler Philipp, Schweda Frank, Georgieff Michael, Warth Richard, Thomas Joerg

Abstract excerpt

The nucleoside adenosine has been implicated in the regulation of respiration, especially during hypoxia in the newborn. In this study the role of adenosine A1 receptors for the control of respiration was investigated in vivo. To this end, respiration of unrestrained adult and neonatal adenosine A1 receptor knockout mice (A1R(-/-)) was measured in a plethysmographic device. Under control conditions (21% O2) and...

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Identifiers

PMID: 26593641
DOI: 10.1016/j.resp.2015.11.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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