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Article

TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.

The European respiratory journal - 1 Nov 2017

Olschewski Andrea, Veale Emma L, Nagy Bence M, Nagaraj Chandran, Kwapiszewska Grazyna, Antigny Fabrice, Lambert Mélanie, Humbert Marc, Czirják Gábor, Enyedi Péter, Mathie Alistair

Abstract excerpt

TWIK-related acid-sensitive potassium channel 1 (TASK-1 encoded by KCNK3) belongs to the family of two-pore domain potassium channels. This gene subfamily is constitutively active at physiological resting membrane potentials in excitable cells, including smooth muscle cells, and has been particularly linked to the human pulmonary circulation. TASK-1 channels are sensitive to a wide array of physiological and...

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Share to Familial Primary Pulmonary Hypertension
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Potentials

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Share to Potassium Channels, Tandem Pore Domain

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Source

Identifiers

PMID: 29122916
DOI: 10.1183/13993003.00754-2017

Genes

KCNK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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