Article

Hepatitis B Virus Demethylates PD-1 and Modulates the Changes of the Tumor Microenvironment in Hepatocellular Carcinoma Patients

2021-08-13

Abstract excerpt

<h4>Background: </h4> Hepatitis B virus (HBV) constitutes a major global health burden. Previously study has found the expression of programmed cell death 1 (PD-1) is up-regulated during the chronic HBV infection. However, the mechanism of how HBV infection modulates the expression of PD-1 on CD8 + T cells are not well understood. In the present study, we aimed to analyzed the role of DNA methylation in regulating...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0adf46dd-36fe-59a0-b591-b39185e64d21
DOI: 10.21203/rs.3.rs-793418/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hepatitis B Virus Demethylates PD-1 and Modulates the Changes of the Tumor Microenvironment in Hepatocellular Carcinoma PatientsDOI 10.21203/rs.3.rs-793418/v1Read

Epigenetic modification of hepatitis B virus infection and related hepatocellular carcinomaSemantic proximity Read

The signature of HBV-related liver disease in peripheral blood mononuclear cell DNA methylationSemantic proximity Read

Epigenetic modulation in chronic hepatitis B virus infectionSemantic proximity Read

A Programmed Cell Death-1 Haplotype is Associated with Clearance of Hepatitis B Virus.Semantic proximity Read

Mechanisms of DNA Methylation in Virus-Host Interaction in Hepatitis B Infection: Pathogenesis and Oncogenetic PropertiesSemantic proximity Read

A comprehensive comparison of molecular and phenotypic profiles between hepatitis B virus (HBV)-infected and non-HBV-infected hepatocellular carcinoma by multi-omics analysis.Semantic proximity Read

Genetic variants of programmed cell death 1 are associated with HBV infection and liver disease progression.Semantic proximity Read

Host Epigenetic Alterations and Hepatitis B Virus-Associated Hepatocellular CarcinomaSemantic proximity Read

Comparative Transcriptomic and Epigenomic Analysis Highlights Hepatitis B Virus Infection Impact on Hepatocellular Carcinoma DevelopmentSemantic proximity Read

Epigenetic mediated functional reprogramming of immune cells leads to HBsAg seroconversion in Hepatitis B Virus Reactivation patientsSemantic proximity Read

The Epigenetic Modulation of Cancer and Immune Pathways in Hepatitis B Virus-Associated Hepatocellular Carcinoma: The Influence of HBx and miRNA DysregulationSemantic proximity Read

Hepatitis B virus-induced hepatocellular carcinoma.Semantic proximity Read