Article
Contribution of trans regulatory eQTL to cryptic genetic variation in C. elegans.
BMC genomics - 29 Jun 2017
Snoek Basten L, Sterken Mark G, Bevers Roel P J, Volkers Rita J M, Van't Hof Arjen, Brenchley Rachel, Riksen Joost A G, Cossins Andrew, Kammenga Jan E
Abstract excerpt
BACKGROUND: Cryptic genetic variation (CGV) is the hidden genetic variation that can be unlocked by perturbing normal conditions. CGV can drive the emergence of novel complex phenotypes through changes in gene expression. Although our theoretical understanding of CGV has thoroughly increased over the past decade, insight into polymorphic gene expression regulation underlying CGV is scarce. Here we investigated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.