Article
Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematode Caenorhabditis remanei.
G3 (Bethesda, Md.) - 15 Apr 2021
O'Connor Christine H, Sikkink Kristin L, Nelson Thomas C, Fierst Janna L, Cresko William A, Phillips Patrick C
Abstract excerpt
The adaptation of complex organisms to changing environments has been a central question in evolutionary quantitative genetics since its inception. The structure of the genotype-phenotype maps is critical because pleiotropic effects can generate widespread correlated responses to selection and potentially restrict the extent of evolutionary change. In this study, we use experimental evolution to dissect the...
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