Article
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans.
PLoS genetics - 29 Dec 2006
Li Yang, Alvarez Olga Alda, Gutteling Evert W, Tijsterman Marcel, Fu Jingyuan, Riksen Joost A G, Hazendonk Esther, Prins Pjotr, Plasterk Ronald H A, Jansen Ritsert C, Breitling Rainer, Kammenga Jan E
Abstract excerpt
Recent genetical genomics studies have provided intimate views on gene regulatory networks. Gene expression variations between genetically different individuals have been mapped to the causal regulatory regions, termed expression quantitative trait loci. Whether the environment-induced plastic response of gene expression also shows heritable difference has not yet been studied. Here we show that differential...
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