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Genetic Variants in the Manganese Superoxide Dismutase 2 Gene and in the Catalase Gene are not Associated With Alcoholic Chronic Pancreatitis.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Sept 2017

Schneider Alexander, Rosendahl Jonas, Bugert Peter, Weiss Christel, Unterschütz Heike, Kylanpää-Bäck Marja-Leena, Lempinen Marko, Kemppainen Esko, Diaconu Brindusa L, Ebert Matthias P, Pfützer Roland H

Abstract excerpt

AIMS: Oxidative stress may contribute to the development of chronic pancreatitis (CP). The enzymes manganese superoxide dismutase 2 (MnSOD, SOD2) and catalase (CAT) counteract free radical activity within the mitochondria and the cytosol. Moreover, CAT activity contributes to the transformation of ethanol to acetaldehyde, a toxic intermediate product of ethanol metabolism, which has been associated with...

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PMID: 28655148
DOI: 10.1093/alcalc/agx039

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CAT
SOD2

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Genetic Variants in the Manganese Superoxide Dismutase 2 Gene and in the Catalase Gene are not Associated With Alcoholic Chronic Pancreatitis.PMID 28655148Read ↗

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