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Article

The role of epoxide hydrolase Y113H gene variant in pancreatic diseases.

Pancreas - 1 May 2009

Ockenga Johann, Strunck Sebastian, Post Cora, Schulz Hans-Ulrich, Halangk Juliane, Pfützer Roland H, Löhr Matthias, Oettle Helmut, Kage Andreas, Rosendahl Jonas, Keim Volker, Drenth Joost P H, Jansen Jan B M J, Lochs Herbert, Witt Heiko

Abstract excerpt

OBJECTIVES: Chronic pancreatitis (CP) and pancreatic adenocarcinoma (pCA) are associated with risk factors such as alcohol intake and tobacco smoking. Microsomal epoxide hydrolase (EPHX1) is a phase II detoxifying enzyme capable of tobacco-borne toxicant inactivation. We studied the role of the EPHX1 c.337T>C (p.Y113H) variant, whichleads to altered enzyme activity, in pancreatic diseases. METHODS: We genotyped...

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Source

Identifiers

PMID: 19287329
DOI: 10.1097/MPA.0b013e31819feeed

Genes

EPHX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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