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Associations between the DBH gene, plasma dopamine β-hydroxylase activity and cognitive measures in Han Chinese patients with schizophrenia.

Schizophrenia research - 1 Mar 2018

Sun Zuoli, Ma Yun, Li Wenbiao, He Jing, Li Jun, Yang Xue, Mao Peixian, Cubells Joseph F, Tang Yi-Lang

Abstract excerpt

The dopamine (DA) and norepinephrine (NE) systems modulate cognitive function. Dopamine β-hydroxylase (DβH) converts DA to NE, and its activity is under strong genetic control. This study examines the association of plasma DβH (pDβH) activity, DBH gene polymorphisms (-1021C>T, rs1611115 and 444G>A, rs1108580) and cognitive deficits in Han Chinese patients with schizophrenia. We assessed pDβH activity and...

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Source

Identifiers

PMID: 28647493
DOI: 10.1016/j.schres.2017.06.028

Genes

DBH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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