Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia.

Journal of psychiatric research - 1 Jun 2012

Hui Li, Zhang Xuan, Huang Xu Feng, Han Mei, Fernandez Francesca, Yu Yaqin, Sun ShiLong, Li Wenjun, Chen Da Chun, Xiu Mei Hong, Kosten Thomas R, Zhang Xiang Yang

Abstract excerpt

BACKGROUND: Numerous studies report dysfunctional dopaminergic and noradrenergic neurotransmission in the pathogenesis of schizophrenia. Dopamine beta-hydroxylase (DBH) is an intracellular enzyme catalyzing the conversion of dopamine to noradrenaline. Functional polymorphisms have been reported in the promoter region of DBH gene, including a 19 bp insertion/deletion polymorphism. The purpose of this study was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Antipsychotic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine beta-Hydroxylase

Share to Logistic Models

Share to Psychiatric Status Rating Scales

Share to Schizophrenia

Share to Sequence Deletion

Share to Young Adult

Source

Identifiers

PMID: 22445279
DOI: 10.1016/j.jpsychires.2012.02.016

Genes

FES
DBH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia.PMID 22445279Read ↗

Association of the dopamine β-hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia.Semantic proximity Read ↗

Association of functional dopamine-beta-hydroxylase (DBH) 19 bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers.Semantic proximity Read ↗

Association between DBH 19 bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients.Semantic proximity Read ↗

Association between the angiotensin-converting enzyme gene insertion/deletion polymorphism and first-episode patients with schizophrenia in a Chinese Han population.Semantic proximity Read ↗

The dopamine beta-hydroxylase gene polymorphism rs1611114 is associated with schizophrenia in the Chinese Zhuang but not Chinese Han population.Semantic proximity Read ↗

Association of Dopamine Beta-Hydroxylase Polymorphisms with Alzheimer’s Disease, Parkinson’s Disease and Schizophrenia: Evidence Based on Currently Available LociSemantic proximity Read ↗

Possible association between DBH 19 bp insertion/deletion polymorphism and clinical symptoms in schizophrenia with tardive dyskinesia.Semantic proximity Read ↗

Association between DBH 19bp insertion/deletion polymorphism and cognition in schizophrenia with and without tardive dyskinesia.Semantic proximity Read ↗

Dopamine beta-hydroxylase (DBH) gene and schizophrenia phenotypic variability: a genetic association study.Semantic proximity Read ↗

Association of tagging single nucleotide polymorphisms on 8 candidate genes in dopaminergic pathway with schizophrenia in Croatian population.Semantic proximity Read ↗

Association of dopamine β-hydroxylase polymorphism rs1611115 and serum levels with psychiatric disorders in Pakistani population.Semantic proximity Read ↗

Association of promoter variants of human dopamine transporter gene with schizophrenia in Han Chinese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.