Article
The dopamine beta-hydroxylase gene polymorphism rs1611114 is associated with schizophrenia in the Chinese Zhuang but not Chinese Han population.
Molecular genetics and genomics : MGG - 1 Oct 2016
Long Jianxiong, Huang Guifeng, Liang Baoyun, Ling Weijun, Guo Xiaojing, Jiang Juan, Su Li
Abstract excerpt
Schizophrenia (SCZ) is a devastating neurodevelopmental disorder. However, the mechanism underlying this highly heritable disorder remains unclear. The dopamine beta-hydroxylase (DBH) gene encodes a key metabolic enzyme of dopamine. Consequently, DBH is considered a candidate gene for SCZ. However, previous studies on its association with SCZ susceptibility have shown conflicting results. Here, we examined...
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