Article
Association of functional dopamine-beta-hydroxylase (DBH) 19 bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers.
Schizophrenia research - 1 Oct 2012
Zhang Xiang Yang, Chen Da Chun, Xiu Mei Hong, Hui Li, Liu Haibo, Luo Xingguang, Zuo Lingjun, Zhang Huiping, Kosten Therese A, Kosten Thomas R
Abstract excerpt
Recent evidence suggests that a dopamine beta-hydroxylase (DBH) polymorphism may play a role in determining an individual's predisposition to developing nicotine dependence. The mechanism for such an association may reflect nicotine's mediation of drug reward in the brain through actions on dopamine, a key mediator of drug reward. Because schizophrenia patients have usually high rates of nicotine use, they are a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.