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Article

Synaptonemal complex formation and meiotic checkpoint signaling are linked to the lateral element protein Red1.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jun 2010

Eichinger Christian S, Jentsch Stefan

Abstract excerpt

Meiosis generates four haploid daughters from a diploid parental cell. Central steps of meiosis are the pairing and recombination of homologous chromosomes followed by their segregation in two rounds of cell division. Meiotic recombination is monitored by a specialized DNA damage checkpoint pathway and is guided by a unique chromosomal structure called synaptonemal complex (SC), but how these events are...

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Identifiers

PMID: 20534433
DOI: 10.1073/pnas.1004248107
PMCID: PMC2895081

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