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Article

Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination.

The Journal of biological chemistry - 6 Jan 2012

Busygina Valeria, Saro Dorina, Williams Gareth, Leung Wing-Kit, Say Amanda F, Sehorn Michael G, Sung Patrick, Tsubouchi Hideo

Abstract excerpt

During meiosis, recombination events that occur between homologous chromosomes help prepare the chromosome pairs for proper disjunction in meiosis I. The concurrent action of the Rad51 and Dmc1 recombinases is necessary for an interhomolog bias. Notably, the activity of Rad51 is tightly controlled, so as to minimize the use of the sister chromatid as recombination partner. We demonstrated recently that Hed1, a...

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Identifiers

PMID: 22115747
DOI: 10.1074/jbc.M111.297309
PMCID: PMC3256901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination.PMID 22115747Read ↗

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