Article
Bcl1 polymorphism of the glucocorticoid receptor gene and treatment response to milnacipran and fluvoxamine in Japanese patients with depression.
Neuropsychobiology - 1 Jan 2014
Takahashi Hitoshi, Yoshida Keizo, Higuchi Hisashi, Kamata Mitsuhiro, Inoue Kazuyuki, Suzuki Toshio, Ishigooka Jun
Abstract excerpt
BACKGROUND: Polymorphisms in the glucocorticoid receptors (GRs) have been widely studied with rather less emphasis on relating their differences with possible pharmacological treatment outcomes. The purpose of this study was to investigate whether Bcl1 polymorphisms of GRs are associated with the antidepressant effect of milnacipran, a serotonin noradrenaline reuptake inhibitor (SNRI), and fluvoxamine, a...
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