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Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA.

Drug discovery today - 1 May 2015

Ahmed Marawan, Wang Feng, Levin Aviad, Le Connie, Eltayebi Yomna, Houghton Michael, Tyrrell Lorne, Barakat Khaled

Abstract excerpt

Chronic infection with hepatitis B virus (HBV) often leads to the development of liver cancer and cirrhosis, creating immense sociological, clinical and economic burdens worldwide. Although current anti-HBV medications manage to control the disease progression and help restore normal liver functi...

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Share to DNA, Circular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25622780
DOI: 10.1016/j.drudis.2015.01.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25622780-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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