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Article

Novel role and regulation of HDAC4 in cocaine-related behaviors.

Addiction biology - 1 Mar 2018

Penrod Rachel D, Carreira Maria B, Taniguchi Makoto, Kumar Jaswinder, Maddox Stephanie A, Cowan Christopher W

Abstract excerpt

Epigenetic mechanisms have been proposed to contribute to persistent aspects of addiction-related behaviors. One family of epigenetic molecules that may regulate maladaptive behavioral changes produced by cocaine use are the histone deacetylases (HDACs)-key regulators of chromatin and gene expression. In particular, the class IIa HDACs (HDAC4, HDAC5, HDAC7 and HDAC9) respond to changes in neuronal activity by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28635037
DOI: 10.1111/adb.12522
PMCID: PMC6515921

Genes

HDAC4
HDAC5
HDAC7
HDAC9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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