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Article

Molecular regulation and dysregulation of T follicular helper cells - learning from inborn errors of immunity.

Current opinion in immunology - 1 Oct 2021

Tangye Stuart G, Ma Cindy S

Abstract excerpt

The production of high-affinity antibodies is a key feature of the vertebrate immune system. Antibodies neutralize and clear pathogens, thereby protecting against infectious diseases. However, dysregulated production of antibodies can cause immune pathologies, such as autoimmunity and immune deficiency. Long-lived humoral immunity depends on B-cell help provided by T follicular helper (Tfh) cells, which support...

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Identifiers

PMID: 34284230
DOI: 10.1016/j.coi.2021.06.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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