Article
ATM, radiation, and the risk of second primary breast cancer.
International journal of radiation biology - 1 Oct 2017
Bernstein Jonine L, Concannon Patrick
Abstract excerpt
PURPOSE: It was first suggested more than 40 years ago that heterozygous carriers for the human autosomal recessive disorder Ataxia-Telangiectasia (A-T) might also be at increased risk for cancer. Subsequent studies have identified the responsible gene, Ataxia-Telangiectasia Mutated (ATM), characterized genetic variation at this locus in A-T and a variety of different cancers, and described the functions of the...
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