Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study.

doi:10.1093/jnci/djq055

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Article

Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study.

Journal of the National Cancer Institute - 7 Apr 2010

Bernstein Jonine L, Haile Robert W, Stovall Marilyn, Boice John D, Shore Roy E, Langholz Bryan, Thomas Duncan C, Bernstein Leslie, Lynch Charles F, Olsen Jorgen H, Malone Kathleen E, Mellemkjaer Lene, Borresen-Dale Anne-Lise, Rosenstein Barry S, Teraoka Sharon N, Diep Anh T, Smith Susan A, Capanu Marinela, Reiner Anne S, Liang Xiaolin, Gatti Richard A, Concannon Patrick

Abstract excerpt

BACKGROUND: Ionizing radiation is a known mutagen and an established breast carcinogen. The ATM gene is a key regulator of cellular responses to the DNA damage induced by ionizing radiation. We investigated whether genetic variants in ATM play a clinically significant role in radiation-induced contralateral breast cancer in women. METHODS: The Women's Environmental, Cancer, and Radiation Epidemiology Study is an...

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PMID: 20305132
DOI: 10.1093/jnci/djq055
PMCID: PMC2902825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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