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Article

The role of ATM in breast cancer development.

Breast cancer research and treatment - 1 Aug 2007

Prokopcova Jana, Kleibl Zdenek, Banwell Claire M, Pohlreich Petr

Abstract excerpt

Complete or partial inability to sense and repair DNA damage increases the risk of developing cancer. The ataxia telangiectasia mutated (ATM) protein kinase has a crucial role in response to DNA double-strand breaks. Hereditary mutations in the ATM gene are the cause of a rare genomic instability syndrome ataxia telangiectasia (AT) characterized, among others, by elevated cancer risk. Although clear in...

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Source

Identifiers

PMID: 17061036
DOI: 10.1007/s10549-006-9406-6

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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