Article
The ATM gene and breast cancer: is it really a risk factor?
Mutation research - 1 Apr 2000
Angèle S, Hall J
Abstract excerpt
The genetic determinants for most breast cancer cases remain elusive. Whilst mutations in BRCA1 and BRCA2 significantly contribute to familial breast cancer risk, their contribution to sporadic breast cancer is low. In such cases genes frequently altered in the general population, such as the gene mutated in Ataxia telangiectasia (AT), ATM may be important risk factors. The initial interest in studying ATM...
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