Article
[Ataxia-telangiectasia mutated gene and breast cancer susceptibility].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Jan 2010
Zhang Nan, Che Jian, Bai Song, Wu Zheng, Cui Yuying, Zou Wei
Abstract excerpt
Breast cancer is bound up with the environment. As a consequence of DNA damage induced by environmental carcinogens, a number of sophisticated sensing and transduction systems are initiated and the signal is conveyed simultaneously to multiple effectors. This process ultimately results in cancer. The protein kinase Ataxia-telangiectasia mutated (ATM) that encoded by ATM gene is the master regulator of DNA damage...
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