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Article

Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells.

Molecular neurobiology - 1 May 2018

Bulloj Ayelen, Maminishkis Arvydas, Mizui Masayuki, Finnemann Silvia C

Abstract excerpt

Semaphorins form a family of secreted and membrane-bound molecules that were identified originally as axonal guidance factors during neuronal development. Given their wide distribution in many including mature tissues, semaphorin 4D (sema4D) and its main functional receptor plexin B1 (plxnB1) are expected to fulfill additional functions that remain to be uncovered. A main characteristic of the plexin receptor...

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Topics

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Share to GTPase-Activating Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phagocytosis

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Share to Receptors, Cell Surface

Share to Retinal Pigment Epithelium

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Source

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Identifiers

PMID: 28624895
DOI: 10.1007/s12035-017-0649-5
PMCID: PMC5733634

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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