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Article

Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis.

Proceedings of the National Academy of Sciences of the United States of America - 17 Jul 2007

Nandrot Emeline F, Anand Monika, Almeida Dena, Atabai Kamran, Sheppard Dean, Finnemann Silvia C

Abstract excerpt

The integrin receptor alphavbeta5 controls two independent forms of interactions of the retinal pigment epithelium (RPE) with adjacent photoreceptor outer segments that are essential for vision. Alphavbeta5 localizes specifically to apical microvilli of the RPE and contributes to retinal adhesion...

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Share to Antigens, Surface
Share to c-Mer Tyrosine Kinase
Share to Integrins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Milk Proteins

Share to Phagocytosis

Share to Pigment Epithelium of Eye

Share to Rod Cell Outer Segment

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Source

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Identifiers

PMID: 17620600
DOI: 10.1073/pnas.0704756104
PMCID: PMC1924559

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17620600-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis.PMID 17620600Read ↗

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