Article
Apolipoprotein E genotype impact on memory and attention in older persons: the moderating role of personality phenotype.
International journal of geriatric psychiatry - 1 Feb 2018
Chapman Benjamin P, Benedict Ralph H B, Lin Feng, Roy Shumita, Porteinsson Antoine, Szigeti Kinga, Federoff Howard, Mapstone Mark
Abstract excerpt
OBJECTIVES: To determine if phenotypic personality traits modify the association of Apolipoprotein E (APOE) genotypes with different domains of cognitive function. DESIGN: Cross-sectional. METHODS: 172 non-demented older adults were administered the NEO-Five Factor Inventory (NEO-FFI), a battery...
Topics
- Aged
- Aged, 80 and over
- Apolipoprotein E4
- Apolipoproteins E
- Attention
- Cognition
- Cross-Sectional Studies
- Executive Function
- Female
- Genotype
- Humans
- Male
- Memory
- Memory Disorders
- Neuropsychological Tests
- Personality
- Phenotype
- Regression Analysis