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Article

Does apolipoprotein E genotype influence cognition in middle-aged individuals?

23 Sept 2015

Abstract excerpt

PURPOSE OF REVIEW: The apolipoprotein ε4 (APOE ε4) allele has been recognized as a risk factor for the late-onset Alzheimer's disease. It may modulate cognitive performance in nondemented younger and older ε4 carriers. Does APOE ε4 genotype affect cognition in mid-aged population as well? In this review, a summary of current evidence concerning the effect of this genotype on cognition in middle-aged individuals...

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Identifiers

PMID: 26402402
DOI: 10.1097/wco.0000000000000262

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