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Article

Aberrant Cx43 Expression and Mislocalization in Metastatic Human Melanomas

1 Jan 2017

Abstract excerpt

At present, it is unclear if melanocytes contain Cx43 gap junctions and whether Cx43 expression is regulated in melanoma onset and progression. To this end, we cultured pure populations of mouse melanocytes and found that they had no detectable Cx43 and exhibited an inability for dye transfer indicating they were devoid of functional gap junctions. Given the evidence that melanomas acquire the expression of other...

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PMID: 28607585
DOI: 10.7150/jca.18569

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