Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study.

doi:10.1200/JCO.2016.71.8585

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Article

Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Aug 2017

Bond Jonathan, Graux Carlos, Lhermitte Ludovic, Lara Diane, Cluzeau Thomas, Leguay Thibaut, Cieslak Agata, Trinquand Amélie, Pastoret Cedric, Belhocine Mohamed, Spicuglia Salvatore, Lheritier Véronique, Leprêtre Stéphane, Thomas Xavier, Huguet Françoise, Ifrah Norbert, Dombret Hervé, Macintyre Elizabeth, Boissel Nicolas, Asnafi Vahid

Abstract excerpt

Purpose Early thymic precursor (ETP) acute lymphoblastic leukemia (ALL) is an immunophenotypically defined subgroup of T-cell ALL (T-ALL) associated with high rates of intrinsic treatment resistance. Studies in children have shown that the negative prognostic impact of chemotherapy resistance is abrogated by the implementation of early response-based intensification strategies. Comparable data in adults are...

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PMID: 28605290
DOI: 10.1200/JCO.2016.71.8585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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