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Article

T-cell Acute Lymphoblastic Leukemia: A Roadmap to Targeted Therapies.

Blood cancer discovery - 1 Jan 2021

Cordo' Valentina, van der Zwet Jordy C G, Canté-Barrett Kirsten, Pieters Rob, Meijerink Jules P P

Abstract excerpt

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy characterized by aberrant proliferation of immature thymocytes. Despite an overall survival of 80% in the pediatric setting, 20% of patients with T-ALL ultimately die from relapsed or refractory disease. Therefore, there is an urgent need for novel therapies. Molecular genetic analyses and sequencing studies have led to the...

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Identifiers

PMID: 34661151
DOI: 10.1158/2643-3230.BCD-20-0093
PMCID: PMC8447273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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