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Article

Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia

18 May 2013

Abstract excerpt

Adult T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic tumor associated with poor outcome. In this study, we analyzed the prognostic relevance of genetic alterations, immunophenotypic markers, and microarray gene expression signatures in a panel of 53 adult T-ALL patients treated in the Eastern Cooperative Oncology Group E2993 clinical trial. An early immature gene expression signature,...

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PMID: 23687089
DOI: 10.1182/blood-2013-03-491092

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