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Article

Pediatric T-cell acute lymphoblastic leukemia.

Genes, chromosomes & cancer - 1 Feb 2017

Karrman Kristina, Johansson Bertil

Abstract excerpt

The most common pediatric malignancy is acute lymphoblastic leukemia (ALL), of which T-cell ALL (T-ALL) comprises 10-15% of cases. T-ALL arises in the thymus from an immature thymocyte as a consequence of a stepwise accumulation of genetic and epigenetic aberrations. Crucial biological processes, such as differentiation, self-renewal capacity, proliferation, and apoptosis, are targeted and deranged by several...

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Identifiers

PMID: 27636224
DOI: 10.1002/gcc.22416

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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