Article
Association of a neuronal nitric oxide synthase gene polymorphism with levodopa-induced dyskinesia in Parkinson's disease.
Nitric oxide : biology and chemistry - 1 Apr 2018
Santos-Lobato Bruno Lopes, Borges Vanderci, Ferraz Henrique Ballalai, Mata Ignacio Fernandez, Zabetian Cyrus P, Tumas Vitor
Abstract excerpt
BACKGROUND: Levodopa-induced dyskinesia (LID) is a common complication of advanced Parkinson's disease (PD). PD physiopathology is associated with dopaminergic and non-dopaminergic pathways, including the nitric oxide system. The present study aims to examine the association of a neuronal nitric oxide synthase gene (NOS1) single nucleotide polymorphism (rs2682826) with LID in PD patients. METHODS AND RESULTS: We...
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