Article
Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia.
Molecular psychiatry - 1 Jan 2002
Shinkai T, Ohmori O, Hori H, Nakamura J
Abstract excerpt
Nitric oxide (NO) has been identified as a widespread and multifunctional biological messenger molecule in the central nervous system (CNS), with possible roles in neurotransmission, neurosecretion, synaptic plasticity, and tissue injury in many neurological disorders, including schizophrenia. Neuronal NO is widely produced in the brain from L-arginine catalyzed by neuronal NO synthase (NOS1). We therefore...
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