Article
Association of rs1285933 single nucleotide polymorphism in CLEC5A gene with dengue severity and its functional effects.
Human immunology - 1 Oct 2017
Xavier-Carvalho Caroline, Cezar Renata Duarte da Silva, Freire Naishe Matos, Vasconcelos Carla Maria Mola de, Solorzano Victor Edgar Fiestas, de Toledo-Pinto Thiago Gomes, Fialho Luciana Gomes, do Carmo Rodrigo Feliciano, Vasconcelos Luydson Richardson Silva, Cordeiro Marli Tenório, Baptista Paulo, de Azeredo Elzinandes Leal, da Cunha Rivaldo Venâncio, de Souza Luiz José, Pacheco Antonio Guilherme, Kubelka Claire Fernandes, Moura Patrícia Muniz Mendes Freire de, Moraes Milton Ozorio
Abstract excerpt
Outbreaks of the Zika, dengue, and chikungunya viruses, especially in the Americas, pose a global threat due to their rapid spread and difficulty controlling the vector. Extreme phenotypes are often observed, from asymptomatic to severe clinical manifestations, which are well-studied in dengue. Host variations are also important contributors to disease outcomes, and many case-control studies have associated...
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