Article
Loci Contributing to Boric Acid Toxicity in Two Reference Populations of Drosophila melanogaster.
G3 (Bethesda, Md.) - 7 Jun 2017
Najarro Michael A, Hackett Jennifer L, Macdonald Stuart J
Abstract excerpt
Populations maintain considerable segregating variation in the response to toxic, xenobiotic compounds. To identify variants associated with resistance to boric acid, a commonly-used household insecticide with a poorly understood mechanism of action, we assayed thousands of individuals from hundreds of strains. Using the Drosophila Synthetic Population Resource (DSPR), a multi-parental population (MPP) of inbred...
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