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Article

Characterization of MED12, HMGA2, and FH alterations reveals molecular variability in uterine smooth muscle tumors.

Molecular cancer - 7 Jun 2017

Mäkinen Netta, Kämpjärvi Kati, Frizzell Norma, Bützow Ralf, Vahteristo Pia

Abstract excerpt

Uterine smooth muscle tumors range from benign leiomyomas to malignant leiomyosarcomas. Based on numerous molecular studies, leiomyomas and leiomyosarcomas mostly lack shared mutations and the majority of tumors are believed to develop through distinct mechanisms. To further characterize the molecular variability among uterine smooth muscle tumors, and simultaneously insinuate their potential malignant...

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Share to Biomarkers, Tumor
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fumarate Hydratase

Share to Gene Expression

Share to HMGA2 Protein

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Share to Uterine Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 28592321
DOI: 10.1186/s12943-017-0672-1
PMCID: PMC5463371

Genes

HMGA2
MED12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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