Article
Integrative information theoretic network analysis for genome-wide association study of aspirin exacerbated respiratory disease in Korean population.
BMC medical genomics - 24 May 2017
Wang Sehee, Jeong Hyun-Hwan, Kim Dokyoon, Wee Kyubum, Park Hae-Sim, Kim Seung-Hyun, Sohn Kyung-Ah
Abstract excerpt
BACKGROUND: Aspirin Exacerbated Respiratory Disease (AERD) is a chronic medical condition that encompasses asthma, nasal polyposis, and hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs. Several previous studies have shown that part of the genetic effects of the disease may be induced by the interaction of multiple genetic variants. However, heavy computational cost as well as the...
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